Reductive cyclization of 6-cyanomethyl-5-nitropyrimidines - an efficient route to 7-alkyl-5H-pyrrolo[3,2-d]pyrimidines and 6-amino-7,7-dialkyl-7H-pyrrolo[3,2-d]primidines. Utilization in the synthesis of 9-deaza analogues of DHPA.-Reference-Cited by-同舟云学术

Reductive cyclization of 6-cyanomethyl-5-nitropyrimidines - an efficient route to 7-alkyl-5H-pyrrolo[3,2-d]pyrimidines and 6-amino-7,7-dialkyl-7H-pyrrolo[3,2-d]primidines. Utilization in the synthesis of 9-deaza analogues of DHPA.

Published:1997-01 Issue:1 Volume:53 Page:391-400
ISSN:0040-4020
Container-title:Tetrahedron
language:en
Short-container-title:Tetrahedron

Author:

Otmar Miroslav,Masojídková Milena,Holý Antonin

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Reference12 articles.

1. ( S )-9-(2,3-Dihydroxypropyl)adenine: An Aliphatic Nucleoside Analog with Broad-Spectrum Antiviral Activity

2. A new synthesis of pyrrolo[3,2-d]pyrimidines ("9-deazapurines") via 3-amino-2-carboalkoxypyrroles

3. Synthesis of "9-deazaguanosine" and other new pyrrolo[3,2-d]pyrimidine C-nucleosides

4. Structure-based design of inhibitors of purine nucleoside phosphorylase. 3. 9-Arylmethyl derivatives of 9-deazaguanine substituted on the arylmethyl group

5. Syntheses of 2″,3″-Dideoxy-L-Glycero-PentofuranosylC-Nucleosides

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1. An Efficient Synthesis of 3H-Pyrrolo[3,2-d]pyrimidin-4(5H)-one Derivatives via an Iminophosphorane;Journal of Heterocyclic Chemistry;2014-04-17

2. Practical one-pot protocol for the syntheses of 2-chloro-pyrrolo[3,2-d]pyrimidines;Tetrahedron;2011-04

3. ChemInform Abstract: Reductive Cyclization of 6-Cyanomethyl-5-nitropyrimidines - An Efficient Route to 7-Alkyl-5H-pyrrolo(3,2-d)pyrimidines and 6-Amino-7, 7-dialkyl-7H-pyrrolo(3,2-d)pyrimidines. Utilization in the Synthesis of 9-Deaza Analogues of DHPA.;ChemInform;2010-08-04

4. Bicyclic 5-6 Systems: Three Heteroatoms 1:2;Comprehensive Heterocyclic Chemistry III;2008

5. Study on the reaction of methylN-Methyl-N-(6-substituted-5-nitropyrimidin-4-yl)glycinates with sodium alkoxides;Journal of Heterocyclic Chemistry;2006-03