Author:
Lee Hyunjoo,Kim Hyoungsu,Baek Seungyoup,Kim Sanghee,Kim Deukjoon
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Reference16 articles.
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3. The ee value of alcohol 5 was determined as >95% by analysis of the 1H NMR spectrum of the corresponding Mosher ester. (a) Vanhessche, K. P. M.; Wang, Z. M.; Sharpless, K. B. Tetrahedron Lett. 1994, 35, 3469–3472; (b) Maier, M. E.; Hermann, C. Tetrahedron 2000, 56, 557–561.
4. Prepared in two steps from known 3-triethylsilylprop-2-yn-1-ol: (1) Red-Al®, Et2O, then IBr, Et2O; (2) DHP, PPTS, CH2Cl2. (a) Denmark, S. E.; Jones, T. K. J. Org. Chem. 1982, 47, 4595–4597; (b) Kim, K. D.; Magriotis, P. A. Tetrahedron Lett. 1990, 31, 6137–6140.
5. An efficient method for the alkynylation of oxiranes using alkynyl boranes
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