Targeting the proinflammatory cytokines, oxidative stress, apoptosis and TGF-β1/STAT-3 signaling by irbesartan to ameliorate doxorubicin-induced hepatotoxicity

Author:

Kabel Ahmed M.,Alzahrani Abdulaziz A.,Bawazir Nawaf M.,Khawtani Rayan O.,Arab Hany H.

Publisher

Elsevier BV

Subject

Infectious Diseases,Pharmacology (medical),Microbiology (medical)

Reference40 articles.

1. Theanine prevents doxorubicin-induced acute hepatotoxicity by reducing intrinsic apoptotic response;Nagai;Food Chem Toxicol,2015

2. Doxorubicin, DNA torsion, and chromatin dynamics;Yang;Biochim Biophys Acta,2014

3. Doxorubicin blocks proliferation of cancer cells through proteolytic activation of CREB3L1;Denard;Elife,2012

4. Protective effect of pravastatin on doxorubicin-induced hepatotoxicity;Mansouri;Bratisl Lek Listy,2017

5. Protective effects of taurine on doxorubicin-induced acute hepatotoxicity through suppression of oxidative stress and apoptotic responses;Nagai;Anticancer Drugs,2016

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