Pharmacokinetics of 4′-cyano-2′-deoxyguanosine, a novel nucleoside analog inhibitor of the resistant hepatitis B virus, in a rat model of chronic kidney disease
Author:
Funder
Japan Agency for Medical Research and Development
Publisher
Elsevier BV
Subject
Infectious Diseases,Pharmacology (medical),Microbiology (medical)
Reference17 articles.
1. Hepatitis B virus infection: prevention of mother-to-child transmission and exacerbation during pregnancy;Sasagawa;J Infect Chemother,2019
2. 7-Deaza-7-fluoro modification confers on 4′-cyano-nucleosides potent activity against entecavir/adefovir-resistant HBV variants and favorable safety;Hayashi;Antivir Res,2020
3. Synthesis and evaluation of the anti-hepatitis B virus activity of 4′-Azido-thymidine analogs and 4′-Azido-2′-deoxy-5-methylcytidine analogs: structural insights for the development of a novel anti-HBV agent;Onitsuka;Nucleos Nucleot Nucleic Acids,2019
4. CMCDG, a novel nucleoside analog with favorable safety features, exerts potent activity against wild-type and entecavir-resistant hepatitis B virus;Higashi-Kuwata;Antimicrob Agents Chemother,2019
5. Design, synthesis, and evaluation of anti-HBV activity of hybrid molecules of entecavir and adefovir: exomethylene acycloguanine nucleosides and their monophosphate derivatives;Imoto;Nucleos Nucleot Nucleic Acids,2015
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