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The Ro Autoantigen Binds Misfolded U2 Small Nuclear RNAs and Assists Mammalian Cell Survival after UV Irradiation

  • Published:2003-12 Issue:24 Volume:13 Page:2206-2211
  • ISSN:0960-9822
  • Container-title:Current Biology
  • language:en
  • Short-container-title:Current Biology

Author:

Chen Xinguo,Smith James D.,Shi Hong,Yang Derek D.,Flavell Richard A.,Wolin Sandra L.

Publisher

Elsevier BV

Subject

General Agricultural and Biological Sciences,General Biochemistry, Genetics and Molecular Biology

Reference21 articles.

1. A lupus-like syndrome develops in mice lacking the Ro 60 kDa protein, a major lupus autoantigen;Xue;Proc. Natl. Acad. Sci. USA,2003

2. A possible role for the 60 kd Ro autoantigen in a discard pathway for defective 5S ribosomal RNA precursors;O'Brien;Genes Dev.,1994

3. Ro ribonucleoproteins contribute to the resistance of Deinococcus radiodurans to ultraviolet irradiation;Chen;Genes Dev.,2000

4. A misfolded form of 5S rRNA is associated with the Ro and La autoantigens;Shi;RNA,1996

5. The levels of the RoRNP-associated Y RNA are dependent upon the presence of ROP-1, the Caenorhabditis elegans Ro60 protein;Labbe;Genetics,1999

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