The 1,25-dihydroxyvitamin D3 (VD) analogues MC903, EB1089 and KH1060 activate the VD receptor: Homodimers show higher ligand sensitivity than heterodimers with retinoid X receptors

Author:

Carlberg Carsten,Mathiasen Ida S.,Saurat Jean-Hilaire,Binderup Lise

Publisher

Elsevier BV

Subject

Cell Biology,Clinical Biochemistry,Endocrinology,Molecular Biology,Molecular Medicine,Biochemistry,Endocrinology, Diabetes and Metabolism

Reference30 articles.

1. Vitamin D: New actions, new analogues, new therapeutic potential;Bikle;Endocrine Rev.,1992

2. Vitamin D3 receptors: structure and function in transcription;Pike;A. Rev. Nutr.,1991

3. The steroid and thyroid hormone receptor superfamily;Evans;Science,1988

4. 1,25(OH)2-vitamin D3 receptors: gene regulation and genetic circuitry;Minghetti;FASEB J.,1988

5. Transcriptional regulation by the nuclear receptor superfamily;Yu;Curr. Opin. Biotech.,1992

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