The metabolism of 2,4-dibromo [6,7-3H]17β-oestradiol in the rat: Ring-A dibromination blocks male-specific 15α-hydroxylation and catechol formation

Author:

Maggs J.L.,Hussain F.,Bulman Page P.C.,Park B.K.

Publisher

Elsevier BV

Subject

Cell Biology,Clinical Biochemistry,Endocrinology,Molecular Biology,Molecular Medicine,Biochemistry,Endocrinology, Diabetes and Metabolism

Reference40 articles.

1. 2-bromo- and 16-bromo-estrogens and related compounds: potential inhibitors for both estradiol 2- and 16α-hydroxylases in rat liver microsomes;Numazawa;J. Steroid Biochem.,1989

2. 2-Fluoroestradiol, separation of estrogenicity from carcinogenicity;Liehr;Molec. Pharmac.,1983

3. The biodistribution of Br-77-labelled estrone: visualization of tissues containing increased estrogen receptors;Spicer;J. Nucl. Med.,1979

4. Estrogen receptor based imaging agents 1. Synthesis and receptor binding affinity of some aromatic and D-ring halogenated estrogens;Heiman;J. Med. Chem.,1980

5. Oxidative metabolism of estradiol;Fishman;J. Biol. Chem.,1960

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