Human endometrial 3β-hydroxysteroid dehydrogenase/isomerase can locally reduce intrinsic estrogenic/progestagenic activity ratios of a steroidal drug (Org OD 14)

Author:

Tang Baiging,Markiewicz Leszek,Kloosterboer Helenius J.,Gurpide Erlio

Publisher

Elsevier BV

Subject

Cell Biology,Clinical Biochemistry,Endocrinology,Molecular Biology,Molecular Medicine,Biochemistry,Endocrinology, Diabetes and Metabolism

Reference22 articles.

1. Clinical profile of Org OD-14;Tax;Maturitas,1987

2. Pharmacological profile of Org OD 14 in experimental animals;Schot,1992

3. Effects of steroid hormones and antiestrogens on alkaline phosphatase activity in human endometrial cancer cells (Ishikawa line);Holinka;Cancer Res.,1986

4. A simple and sensitive microtiter plate estrogen bioassay based on stimulation of alkaline phosphatase in Ishikawa cells: estrogenic action of Δ5 adrenal steroids;Littlefield;Endocrinology,1990

5. Intrinsic estrogenicity of some progestagenic drugs;Markiewicz;J. Steroid Biochem. Molec. Biol.,1992

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