Bridging Weak Links in Mechanistic Modeling: Approach and Application in CHO Cell Cultivation for mAb Production

Author:

Okamura Kozue,Badr Sara,Sugiyama Hirokazu

Publisher

Elsevier

Reference9 articles.

1. Hybrid modelling and data-driven parameterization of monoclonal antibody cultivation processes: Shifts in cell metabolic behavior;Badr;Computer Aided Chemical Engineering.,2023

2. Integrated design of biopharmaceutical manufacturing processes: Operation modes and process configurations for monoclonal antibody production;Badr;Computers and Chemical Engineering,2021

3. Density-based clustering based on hierarchical density estimates;Campello;Advances in Knowledge Discovery and Data Mining,2013

4. A framework for the development of integrated and computationally feasible models of large-scale mammalian cell bioreactors;Farzan;Processes,2018

5. Establishment of a novel CHO cell line and its application to the production of protein-based pharmaceuticals (In Japanese);Horiuchi;Seibutsu-Kougaku-Kaishi,2019

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