The science of finding drug molecules II: demonstrating target engagement and therapeutic value
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Elsevier
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5. H.-C. Eichler, E. Abadie, A. Breckenridge, B. Flamion, L.L. Gustafsson, H. Leufkens. Bridging the efficacy–effectiveness gap: a regulator’s perspective on addressing variability of drug response. Nat. Rev. Drug Discov. 10 (2011) 495–506.
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