Sustained release system for highly water-soluble radiosensitizer drug etanidazole: irradiation and degradation studies

Author:

Yip Ee Ying,Wang Jianjun,Wang Chi-Hwa

Publisher

Elsevier BV

Subject

Mechanics of Materials,Biomaterials,Biophysics,Ceramics and Composites,Bioengineering

Reference20 articles.

1. Radiobiology for the radiologist, Ed 799-91;Hall,1978

2. Clinical trials of radiosensitizers;Brown;Int J Radiat Oncol Biol Phys,1984

3. Relationship between the neurotoxicity of the hypoxic cell radiosensitizer SR2508 and the pharmacokinetic profile;Coleman;Cancer Res,1987

4. The efficacy of pharmacokinetic monitoring and dose modification of etanidazole on the incidence of neurotoxicity—Results from a phase II trial of etanidazole and radiation therapy in locally advanced prostate-cancer;Coleman;Int J Radiat Oncol Biol Phys,1992

5. Radiosensitization of a mouse tumor model by sustained intra-tumoral release of Etanidazole and Tirapazamine using a biodegradable polymer implant device;Yapp;Radiother Oncol,1999

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