SOX2 Is the Determining Oncogenic Switch in Promoting Lung Squamous Cell Carcinoma from Different Cells of Origin

Author:

Ferone Giustina,Song Ji-Ying,Sutherland Kate D.,Bhaskaran Rajith,Monkhorst Kim,Lambooij Jan-Paul,Proost Natalie,Gargiulo Gaetano,Berns Anton

Funder

WKO

Dutch Cancer Society

Synergy ERC

National Health and Medical Research Council

Victorian State Government Operational Infrastructure

Australian Government IRIISS

Worldwide Cancer Research

Publisher

Elsevier BV

Subject

Cancer Research,Cell Biology,Oncology

Reference58 articles.

1. The type 2 cell as progenitor of alveolar epithelial regeneration. A cytodynamic study in mice after exposure to oxygen;Adamson;Lab. Invest.,1974

2. SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas;Bass;Nat. Genet.,2009

3. SOX2 controls tumour initiation and cancer stem-cell functions in squamous-cell carcinoma;Boumahdi;Nature,2014

4. Morphologic and clinicopathologic features of lung squamous cell carcinomas expressing Sox2;Brcic;Am. J. Clin. Pathol.,2012

5. Comprehensive genomic characterization of squamous cell lung cancers;Cancer Genome Atlas Research Network;Nature,2012

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