Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS-Reference-Cited by-同舟云学术

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Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS

Published:2018-03 Issue:3 Volume:33 Page:386-400.e5
ISSN:1535-6108
Container-title:Cancer Cell
language:en
Short-container-title:Cancer Cell

Author:

Yamauchi Takuji,Masuda Takeshi,Canver Matthew C.,Seiler Michael,Semba Yuichiro,Shboul Mohammad,Al-Raqad Mohammed,Maeda Manami,Schoonenberg Vivien A.C.,Cole Mitchel A.,Macias-Trevino Claudio,Ishikawa Yuichi,Yao Qiuming,Nakano Michitaka,Arai Fumio,Orkin Stuart H.,Reversade Bruno,Buonamici Silvia,Pinello Luca,Akashi Koichi,Bauer Daniel E.,Maeda Takahiro

Funder

JSPS

NIDDK

Strategic Positioning Fund

NIH

NHLBI

Burroughs Wellcome Fund

American Society of Hematology

JSPS Grant-in-Aid for Scientific Research

American Cancer Society

Publisher

Elsevier BV

Subject

Cancer Research,Cell Biology,Oncology

Reference70 articles.

1. Mutations in PCSK9 cause autosomal dominant hypercholesterolemia;Abifadel;Nat. Genet.,2003

2. Mutations in DCPS and EDC3 in autosomal recessive intellectual disability indicate a crucial role for mRNA decapping in neurodevelopment;Ahmed;Hum. Mol. Genet.,2015

3. Signatures of mutational processes in human cancer;Alexandrov;Nature,2013

4. The human cap-binding complex is functionally connected to the nuclear RNA exosome;Andersen;Nat. Struct. Mol. Biol.,2013

5. Towards systematic functional characterization of cancer genomes;Boehm;Nat. Rev. Genet.,2011

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