Removal of N-Linked Glycosylation Enhances PD-L1 Detection and Predicts Anti-PD-1/PD-L1 Therapeutic Efficacy-Reference-Cited by-同舟云学术

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Removal of N-Linked Glycosylation Enhances PD-L1 Detection and Predicts Anti-PD-1/PD-L1 Therapeutic Efficacy

Published:2019-08 Issue:2 Volume:36 Page:168-178.e4
ISSN:1535-6108
Container-title:Cancer Cell
language:en
Short-container-title:Cancer Cell

Author:

Lee Heng-Huan,Wang Ying-Nai,Xia Weiya,Chen Chia-Hung,Rau Kun-Ming,Ye Leiguang,Wei Yongkun,Chou Chao-Kai,Wang Shao-Chun,Yan Meisi,Tu Chih-Yen,Hsia Te-Chun,Chiang Shu-Fen,Chao K.S. Clifford,Wistuba Ignacio I.,Hsu Jennifer L.,Hortobagyi Gabriel N.,Hung Mien-Chie

Funder

Ruth Leggett Distinguished Chair Endowment

MDA Startup Fund

University of Texas MD Anderson

China Medical University, Taiwan

Hospital Sister Institution Fund

Breast Cancer Research Foundation

Cancer Prevention and Research Institute of Texas

T32 Training Grant

Ministry of Health and Welfare

China Medical University Hospital Cancer Research Center of Excellence

Ministry of Education

NIH

Center for Biological Pathways

Publisher

Elsevier BV

Subject

Cancer Research,Cell Biology,Oncology

Reference42 articles.

1. A review of guidelines for lung cancer;Bironzo;J. Thorac. Dis.,2018

2. Nivolumab versus docetaxel in advanced nonsquamous non-small-cell lung cancer;Borghaei;N. Engl. J. Med.,2015

3. Nivolumab versus docetaxel in advanced squamous-cell non-small-cell lung cancer;Brahmer;N. Engl. J. Med.,2015

4. Patient selection for anti-PD-1/PD-L1 therapy in advanced non-small-cell lung cancer: implications for clinical practice;Califano;Future Oncol.,2018

5. Anti-PD-1/PD-L1 therapy of human cancer: past, present, and future;Chen;J. Clin. Invest.,2015

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1. ALG3 predicts poor prognosis and increases resistance to anti-PD-1 therapy through modulating PD-L1 N-link glycosylation in TNBC;International Immunopharmacology;2024-10

2. A functional role for glycosylated B7-H5/VISTA immune checkpoint protein in metastatic clear cell renal cell carcinoma;iScience;2024-09

3. New horizons in the mechanisms and therapeutic strategies for PD-L1 protein degradation in cancer;Biochimica et Biophysica Acta (BBA) - Reviews on Cancer;2024-09

4. Ginsenoside Rg3 targets glycosylation of PD-L1 to enhance anti-tumor immunity in non-small cell lung cancer;Frontiers in Immunology;2024-08-23

5. Glycosylation: mechanisms, biological functions and clinical implications;Signal Transduction and Targeted Therapy;2024-08-05

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