Combination of Hypoglycemia and Metformin Impairs Tumor Metabolic Plasticity and Growth by Modulating the PP2A-GSK3β-MCL-1 Axis-Reference-Cited by-同舟云学术

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Combination of Hypoglycemia and Metformin Impairs Tumor Metabolic Plasticity and Growth by Modulating the PP2A-GSK3β-MCL-1 Axis

Published:2019-05 Issue:5 Volume:35 Page:798-815.e5
ISSN:1535-6108
Container-title:Cancer Cell
language:en
Short-container-title:Cancer Cell

Author:

Elgendy Mohamed,Cirò Marco,Hosseini Amir,Weiszmann Jakob,Mazzarella Luca,Ferrari Elisa,Cazzoli Riccardo,Curigliano Giuseppe,DeCensi Andrea,Bonanni Bernardo,Budillon Alfredo,Pelicci Pier Giuseppe,Janssens Veerle,Ogris Manfred,Baccarini Manuela,Lanfrancone Luisa,Weckwerth Wolfram,Foiani Marco,Minucci Saverio

Funder

European Union's Seventh Framework Programme

INDICAR

AIRC

Italian Ministery of Health

DIVA

Publisher

Elsevier BV

Subject

Cancer Research,Cell Biology,Oncology

Reference49 articles.

1. Metformin targets c-MYC oncogene to prevent prostate cancer;Akinyeke;Carcinogenesis,2013

2. Role of protein phosphatase-2A and -1 in the regulation of GSK-3, cdk5 and cdc2 and the phosphorylation of tau in rat forebrain;Bennecib;FEBS Lett.,2000

3. Metabolic determinants of cancer cell sensitivity to glucose limitation and biguanides;Birsoy;Nature,2014

4. Dual effect of metformin on breast cancer proliferation in a randomized presurgical trial;Bonanni;J. Clin. Oncol.,2012

5. Activation of protein phosphatase 2A tumor suppressor as potential treatment of pancreatic cancer;Chien;Mol. Oncol.,2015

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