Inhibition of the Glycolytic Activator PFKFB3 in Endothelium Induces Tumor Vessel Normalization, Impairs Metastasis, and Improves Chemotherapy-Reference-Cited by-同舟云学术

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Inhibition of the Glycolytic Activator PFKFB3 in Endothelium Induces Tumor Vessel Normalization, Impairs Metastasis, and Improves Chemotherapy

Published:2016-12 Issue:6 Volume:30 Page:968-985
ISSN:1535-6108
Container-title:Cancer Cell
language:en
Short-container-title:Cancer Cell

Author:

Cantelmo Anna Rita,Conradi Lena-Christin,Brajic Aleksandra,Goveia Jermaine,Kalucka Joanna,Pircher Andreas,Chaturvedi Pallavi,Hol Johanna,Thienpont Bernard,Teuwen Laure-Anne,Schoors Sandra,Boeckx Bram,Vriens Joris,Kuchnio Anna,Veys Koen,Cruys Bert,Finotto Lise,Treps Lucas,Stav-Noraas Tor Espen,Bifari Francesco,Stapor Peter,Decimo Ilaria,Kampen Kim,De Bock Katrien,Haraldsen Guttorm,Schoonjans Luc,Rabelink Ton,Eelen Guy,Ghesquière Bart,Rehman Jalees,Lambrechts Diether,Malik Asrar B.,Dewerchin Mieke,Carmeliet Peter

Funder

Research Foundation Flanders

Erasmus Mundus, ERAWEB fellowship

Else Kroener-Fresenius-Stiftung

Austrian Science Fund

Agency for Innovation by Science and Technology, Flanders

Bettencourt Schueller Foundation

NIH

Belgian Science Policy

FWO

Foundation Leducq Transatlantic Network

Foundation against Cancer

European Research Council

Advanced Research Grant

AXA Research grant

Publisher

Elsevier BV

Subject

Cancer Research,Cell Biology,Oncology

Reference29 articles.

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3. Downregulation of N-cadherin in the neointima stimulates migration of smooth muscle cells by RhoA deactivation;Blindt;Cardiovasc. Res.,2004

4. Bidirectional induction of the cognate receptor-ligand alpha4/VCAM-1 pair defines a novel mechanism of tumor intravasation;Bogetto;Blood,2000

5. Actin dynamics counteract membrane tension during clathrin-mediated endocytosis;Boulant;Nat. Cell Biol.,2011

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1. Transcription Factor MAZ Potentiates the Upregulated NEIL3-mediated Aerobic Glycolysis, thereby Promoting Angiogenesis in Hepatocellular Carcinoma;Current Cancer Drug Targets;2024-12

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3. Pathogenic role of PFKFB3 in endothelial inflammatory diseases;Frontiers in Molecular Biosciences;2024-09-10

4. Unlocking the potential: Targeting metabolic pathways in the tumor microenvironment for Cancer therapy;Biochimica et Biophysica Acta (BBA) - Reviews on Cancer;2024-09

5. Targeting the tumour vasculature: from vessel destruction to promotion;Nature Reviews Cancer;2024-08-29

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