GPC2-CAR T cells tuned for low antigen density mediate potent activity against neuroblastoma without toxicity-Reference-Cited by-同舟云学术

GPC2-CAR T cells tuned for low antigen density mediate potent activity against neuroblastoma without toxicity

Published:2022-01 Issue:1 Volume:40 Page:53-69.e9
ISSN:1535-6108
Container-title:Cancer Cell
language:en
Short-container-title:Cancer Cell

Author:

Heitzeneder Sabine,Bosse Kristopher R.,Zhu Zhongyu,Zhelev Doncho,Majzner Robbie G.,Radosevich Molly T.,Dhingra Shaurya^ORCID,Sotillo Elena,Buongervino Samantha^ORCID,Pascual-Pasto Guillem,Garrigan Emily,Xu Peng,Huang Jing,Salzer Benjamin^ORCID,Delaidelli Alberto,Raman Swetha,Cui Hong,Martinez Benjamin,Bornheimer Scott J.,Sahaf Bita,Alag Anya^ORCID,Fetahu Irfete S.^ORCID,Hasselblatt Martin^ORCID,Parker Kevin R.^ORCID,Anbunathan Hima^ORCID,Hwang Jennifer,Huang Min,Sakamoto Kathleen,Lacayo Norman J.^ORCID,Klysz Dorota D.^ORCID,Theruvath Johanna,Vilches-Moure José G.,Satpathy Ansuman T.,Chang Howard Y.,Lehner Manfred,Taschner-Mandl Sabine^ORCID,Julien Jean-Phillipe,Sorensen Poul H.,Dimitrov Dimiter S.,Maris John M.,Mackall Crystal L.

Publisher

Elsevier BV

Subject

Cancer Research,Cell Biology,Oncology

Reference48 articles.

1. Distinct features of doublecortin as a marker of neuronal migration and its implications in cancer cell mobility;Ayanlaja;Front. Mol. Neurosci.,2017

2. Advances in the translational genomics of neuroblastoma: from improving risk stratification and revealing novel biology to identifying actionable genomic alterations;Bosse;Cancer,2016

3. Identification of GPC2 as an oncoprotein and candidate immunotherapeutic target in high-risk neuroblastoma;Bosse;Cancer Cell,2017

4. Regression of glioblastoma after chimeric antigen receptor T-cell therapy;Brown;N. Engl. J. Med.,2016

5. Identification of a Titin-derived HLA-A1-presented peptide as a cross-reactive target for engineered MAGE A3-directed T cells;Cameron;Sci. Transl. Med.,2013

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