Disruption of the β1L Isoform of GABP Reverses Glioblastoma Replicative Immortality in a TERT Promoter Mutation-Dependent Manner-Reference-Cited by-同舟云学术

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Disruption of the β1L Isoform of GABP Reverses Glioblastoma Replicative Immortality in a TERT Promoter Mutation-Dependent Manner

Published:2018-09 Issue:3 Volume:34 Page:513-528.e8
ISSN:1535-6108
Container-title:Cancer Cell
language:en
Short-container-title:Cancer Cell

Author:

Mancini Andrew,Xavier-Magalhães Ana,Woods Wendy S.,Nguyen Kien-Thiet,Amen Alexandra M.,Hayes Josie L.,Fellmann Christof,Gapinske Michael,McKinney Andrew M.,Hong Chibo,Jones Lindsey E.,Walsh Kyle M.,Bell Robert J.A.,Doudna Jennifer A.,Costa Bruno M.,Song Jun S.,Perez-Pinera Pablo,Costello Joseph F.

Funder

Dabbiere family

the Hana Jabsheh Research Initiative

NIH

Fundação para a Ciência e Tecnologia

Howard Hughes Medical Institute

Publisher

Elsevier BV

Subject

Cancer Research,Cell Biology,Oncology

Reference70 articles.

1. Long-range chromatin interactions drive mutant Tert promoter activation;Akincilar;Cancer Discov.,2016

2. Upregulating mutations in the TERT promoter commonly occur in adult malignant gliomas and are strongly associated with total 1p19q loss;Arita;Acta Neuropathol.,2013

3. Telomerase inhibition abolishes the tumorigenicity of pediatric ependymoma tumor-initiating cells;Barszczyk;Acta Neuropathol.,2014

4. Cancer. The transcription factor GABP selectively binds and activates the mutant TERT promoter in cancer;Bell;Science,2015

5. Understanding TERT promoter mutations: a common path to immortality;Bell;Mol. Cancer Res.,2016

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1. Advancements in Telomerase-Targeted Therapies for Glioblastoma: A Systematic Review;International Journal of Molecular Sciences;2024-08-09

2. IMPDH Inhibition Decreases TERT Expression and Synergizes the Cytotoxic Effect of Chemotherapeutic Agents in Glioblastoma Cells;International Journal of Molecular Sciences;2024-05-30

3. Prognostic Impact of TERT Promoter Mutations in Adult-Type Diffuse Gliomas Based on WHO2021 Criteria;Cancers;2024-05-27

4. A radiomics‐based nomogram may be useful for predicting telomerase reverse transcriptase promoter mutation status in adult glioblastoma;Brain and Behavior;2024-05

5. Therapeutic targeting of PLK1 in TERT promoter‐mutant hepatocellular carcinoma;Clinical and Translational Medicine;2024-05

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