Microbially Driven TLR5-Dependent Signaling Governs Distal Malignant Progression through Tumor-Promoting Inflammation

Author:

Rutkowski Melanie R.,Stephen Tom L.,Svoronos Nikolaos,Allegrezza Michael J.,Tesone Amelia J.,Perales-Puchalt Alfredo,Brencicova Eva,Escovar-Fadul Ximena,Nguyen Jenny M.,Cadungog Mark G.,Zhang Rugang,Salatino Mariana,Tchou Julia,Rabinovich Gabriel A.,Conejo-Garcia Jose R.

Publisher

Elsevier BV

Subject

Cancer Research,Cell Biology,Oncology

Reference26 articles.

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2. Human TLRs and IL-1Rs in host defense: natural insights from evolutionary, epidemiological, and clinical genetics;Casanova;Annu. Rev. Immunol.,2011

3. Recognition of peptidoglycan from the microbiota by Nod1 enhances systemic innate immunity;Clarke;Nat. Med.,2010

4. Tumor-infiltrating dendritic cell precursors recruited by a beta-defensin contribute to vasculogenesis under the influence of Vegf-A;Conejo-Garcia;Nat. Med.,2004

5. Polyethylenimine-based siRNA nanocomplexes reprogram tumor-associated dendritic cells via TLR5 to elicit therapeutic antitumor immunity;Cubillos-Ruiz;J. Clin. Invest.,2009

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