Engineering CAR-T Cells for Next-Generation Cancer Therapy
Author:
Funder
Cancer Research Institute
Parker Institute for Cancer Immunotherapy
Publisher
Elsevier BV
Subject
Cancer Research,Cell Biology,Oncology
Reference184 articles.
1. IL-7 and CCL19 expression in CAR-T cells improves immune cell infiltration and CAR-T cell survival in the tumor;Adachi;Nat. Biotechnol.,2018
2. IL15 enhances CAR-T cell antitumor activity by reducing mTORC1 activity and preserving their stem cell memory phenotype;Alizadeh;Cancer Immunol. Res.,2019
3. Engineered tumor-targeted T cells mediate enhanced anti-tumor efficacy both directly and through activation of the endogenous immune system;Avanzi;Cell Rep.,2018
4. Human CD8 T cells generated in vitro from hematopoietic stem cells are functionally mature;Awong;BMC Immunol.,2011
5. The UniCAR system: a modular CAR T cell approach to improve the safety of CAR T cells;Bachmann;Immunol. Lett.,2019
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