Expression of chimeric antigen receptor therapy targets detected by single-cell sequencing of normal cells may contribute to off-tumor toxicity-Reference-Cited by-同舟云学术

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Expression of chimeric antigen receptor therapy targets detected by single-cell sequencing of normal cells may contribute to off-tumor toxicity

Published:2021-12 Issue:12 Volume:39 Page:1558-1559
ISSN:1535-6108
Container-title:Cancer Cell
language:en
Short-container-title:Cancer Cell

Author:

Jing Ying,Liu Yuan,Li Qiang,Ye Youqiong,Diao Lixia,Huang Yun,Zhou Yubin,Green Michael R.,Mills Gordon B.,Han Leng

Funder

Welch Foundation

Cancer Prevention and Research Institute of Texas

Publisher

Elsevier BV

Subject

Cancer Research,Cell Biology,Oncology

Reference10 articles.

1. Integrative Bulk and Single-Cell Profiling of Premanufacture T-cell Populations Reveals Factors Mediating Long-Term Persistence of CAR T-cell Therapy;Chen;Cancer Discov.,2021

2. Characteristics of anti-CD19 CAR T cell infusion products associated with efficacy and toxicity in patients with large B cell lymphomas;Deng;Nat. Med.,2020

3. Understanding and treating the inflammatory adverse events of cancer immunotherapy;Dougan;Cell,2021

4. Phase I Study of Chimeric Antigen Receptor-Modified T Cells in Patients with EGFR-Positive Advanced Biliary Tract Cancers;Guo;Clin. Cancer Res.,2018

5. Construction of a human cell landscape at single-cell level;Han;Nature,2020

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1. A scalable computational framework for annotation-independent combinatorial target identification in scRNA-seq databases;2024-06-28

2. Deciphering the tumor immune microenvironment from a multidimensional omics perspective: insight into next-generation CAR-T cell immunotherapy and beyond;Molecular Cancer;2024-06-26

3. Aptamer-Based Nongenetic Reprogramming of CARs Enables Flexible Modulation of T Cell-Mediated Tumor Immunotherapy;ACS Central Science;2024-03-21

4. Harnessing the Transcriptional Signatures of CAR-T-Cells and Leukemia/Lymphoma Using Single-Cell Sequencing Technologies;International Journal of Molecular Sciences;2024-02-19

5. Engineering Challenges and Opportunities in Autologous Cellular Cancer Immunotherapy;The Journal of Immunology;2024-01-15

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