1. The problem of the evolution of metabolic pathways and the controls of such systems is outside the scope of this chapter and will not be considered.
2. Evidence suggesting a non-random character to nucleotide replacements in naturally occurring mutations
3. EVOLUTIONARY VARIABILITY OF CYTOCHROME C PRIMARY STRUCTURES
4. The genome also determines the sequences of RNA molecules that are involved in the mechanism of protein synthesis, i.e., the various types of transfer RNA and ribosomal RNA. Little is known at present regarding the evolution of such molecules, although it is already evident that species differences do exist and that selection must operate on these products of the genome also.
5. “ Organizational Biosynthesis.”,1967