In vitro inhibitory effects of selumetinib on activity of human UDP-glucuronosyltransferases and prediction of in vivo drug-drug interactions

Author:

Yin Hang,Lv Xin,Wang Zhen,Xiao Shichao,Liang Jiaqi,Sun Jie,Jiang Lili,Liu Yong

Funder

National Natural Science Foundation of China

Publisher

Elsevier BV

Reference43 articles.

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3. The effect of propranolol on paracetamol metabolism in man;Baraka;Br. J. Clin. Pharmacol.,1990

4. Inactivation of androgens by UDP-glucuronosyltransferase enzymes in humans;Bélanger;Trends Endocrinol. Metab.,2003

5. Clinical pharmacokinetics and pharmacodynamics of selumetinib;Campagne;Clin. Pharmacokinet.,2021

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