Tissue specific induction of cytochrome P450 (CYP) 1A1 and 1B1 in rat liver and lung following in vitro (tissue slice) and in vivo exposure to benzo(a)pyrene

Author:

Harrigan Jeanine A.,McGarrigle Barbara P.,Sutter Thomas R.,Olson James R.

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference35 articles.

1. Agency for Toxic Substances and Disease Registry (ATSDR). (1995). Toxicological Profile for Polycyclic Aromatic Hydrocarbons. ATSDR, Atlanta.

2. Ah receptor regulation of CYP1B1 expression in primary mouse embryo-derived cells;Alexander;Cancer Research,1997

3. Cytochrome P450-null mice;Buters;Drug Metababolism Reviews,1999

4. Validation of precision-cut liver slices in dynamic organ culture as an in vitro model for studying CYP1A1 and CYP1A2 induction;Drahushuk;Toxicology and Applied Pharmacology,1996

5. Time- and concentration-dependent induction of CYP1A1 and CYP1A2 in precision-cut rat liver slices incubated in dynamic organ culture in the presence of 2,3,7,8-tetrachlorodibenzo-p-dioxin;Drahushuk;Toxicology and Applied Pharmacology,1999

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