Successful prevalidation of the slug mucosal irritation test to assess the eye irritation potency of chemicals

Author:

Adriaens E.,Bytheway H.,De Wever B.,Eschrich D.,Guest R.,Hansen E.,Vanparys P.,Schoeters G.,Warren N.,Weltens R.,Whittingham A.,Remon J.P.

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference35 articles.

1. Adriaens, E., 2006. The slug mucosal irritation assay: an alternative assay for local tolerance testing. National Centre for the Replacement, Refinement and the Reduction of Animals in Research, pp. 1–9.

2. Gastropods as an evaluation tool for screening the irritating potency of absorption enhancers and drugs;Adriaens;Pharmaceutical Research,1999

3. The evaluation of an alternative mucosal irritation test using slugs;Adriaens;Toxicology and Applied Pharmacology,2002

4. Adriaens, E., Remon, J.P., 2007. Evaluation of the stinging and burning properties of some commercial eye preparation with the slug mucosal irritation (SMI) test. In: 6th World Congress on Alternatives and Animal Use in the Life Sciences, Tokyo, Japan.

5. Evaluation of the mucosal irritation potency of co-spray dried amioca/poly(acrylic acid) and amioca/carbopol 974P mixtures;Adriaens;Journal of Controlled Release,2003

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