The mechanism of thrombocytopenia caused by cholesterol-conjugated antisense oligonucleotides

Author:

Harada Kosuke,Furukawa Hideki,Kohara Hiroshi,Nishimura Koki,Komori Hisakazu,Okai Yoshiko,Arai Yuta,Yamamoto Yuhei,Yamamoto Katsuhiko,Imanishi Akio,Shinozawa Tadahiro

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference22 articles.

1. Emerging oligonucleotide therapeutics for rare neuromuscular diseases;Aoki;J. Neuromuscul. Dis.,2021

2. Drug-associated thrombocytopenia;Bakchoul;Hematol. Am. Soc. Hematol. Educ. Program.,2018

3. Cellular uptake and trafficking of antisense oligonucleotides;Crooke;Nat. Biotechnol.,2017

4. Phosphorothioate modified oligonucleotide-protein interactions;Crooke;Nucleic Acids Res.,2020

5. Drug-induced thrombocytopenia: focus on platelet apoptosis;De Silva;Chem. Biol. Interact.,2018

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