Dosing metric in cellular experiments: The mol/cell metric has its limitations
Author:
Funder
National Research Centre
Publisher
Elsevier BV
Subject
Toxicology,General Medicine
Reference18 articles.
1. PINK1 depletion sensitizes non-small cell lung cancer to glycolytic inhibitor 3-bromopyruvate: involvement of ROS and mitophagy;Dai;Pharmacol. Rep.,2019
2. Bioorthogonal profiling of a cancer cell proteome identifies a large set of 3-Bromopyruvate targets beyond glycolysis;Darabedian;ACS Chem. Biol.,2018
3. Moles of a substance per cell is a highly informative dosing metric in cell culture;Doskey;PLoS One,2015
4. Tumor energy metabolism and potential of 3-Bromopyruvate as an inhibitor of aerobic glycolysis: implications in tumor treatment;Fan;Cancers (Basel),2019
5. Dose metric considerations in in vitro assays to improve quantitative in vitro-in vivo dose extrapolations;Groothuis;Toxicology,2015
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1. Effect of 6-hydroxydopamine increase the glutathione level in SH-SY5Y human neuroblastoma cells;Acta Biochimica Polonica;2023-06-01
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