Rebamipide suppresses 5-fluorouracil-induced cell death via the activation of Akt/mTOR pathway and regulates the expression of Bcl-2 family proteins-Reference-Cited by-同舟云学术

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Rebamipide suppresses 5-fluorouracil-induced cell death via the activation of Akt/mTOR pathway and regulates the expression of Bcl-2 family proteins

Published:2018-02 Issue: Volume:46 Page:284-293
ISSN:0887-2333
Container-title:Toxicology in Vitro
language:en
Short-container-title:Toxicology in Vitro

Author:

Tsubaki Masanobu,Takeda Tomoya,Asano Ryo-ta,Matsuda Tomoyuki,Fujimoto Shin-ichiro,Itoh Tatsuki,Imano Motohiro,Satou Takao,Nishida Shozo

Funder

Grant-in-Aid for Scientific Research

Japan Society for the Promotion of Science

Ministry of Education, Culture, Sports, Science and Technology

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference43 articles.

1. Oral mucositis induced by anticancer therapies;Al-Ansari;Curr. Oral Health Rep.,2015

2. Rebamipide: overview of its mechanisms of action and efficacy in mucosal protection and ulcer healing;Arakawa;Dig. Dis. Sci.,1998

3. 15th anniversary of rebamipide: looking ahead to the new mechanisms and new applications;Arakawa;Dig. Dis. Sci.,2005

4. Obesity hormone leptin induces growth and interferes with the cytotoxic effects of 5-fluorouracil in colorectal tumor stem cells;Bartucci;Endocr. Relat. Cancer,2010

5. Effects of palifermin on antitumor activity of chemotherapeutic and biological agents in human head and neck and colorectal carcinoma xenograft models;Brake;Mol. Cancer Res.,2008

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1. Orally Administrated Glutamate Restored EAAT1 and 3 Expression Levels Suppressed in 5-Fluorouracil-damaged Intestinal Epithelial Cells;Anticancer Research;2024-02-29

2. ALLEVIATIVE EFFECTS OF GLUTAMATE AGAINST CHEMOTHERAPEUTIC AGENT-INDUCED INTESTINAL MUCOSITIS;J PHYSIOL PHARMACOL;2022

3. Influence of 6-shogaol potentiated on 5-fluorouracil treatment of liver cancer by promoting apoptosis and cell cycle arrest by regulating AKT/mTOR/MRP1 signalling;Chinese Journal of Natural Medicines;2022-05

4. Oxidative Stress and Chemoradiation-Induced Oral Mucositis: A Scoping Review of In Vitro, In Vivo and Clinical Studies;International Journal of Molecular Sciences;2022-04-27

5. Synergistic Cytotoxicity Effect of 5-fluorouracil and SHP2 Inhibitor Demethylincisterol A3 on Cervical Cancer Cell;Anti-Cancer Agents in Medicinal Chemistry;2021-07-08

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