Human ileal organoid model recapitulates clinical incidence of diarrhea associated with small molecule drugs
Author:
Publisher
Elsevier BV
Subject
Toxicology,General Medicine
Reference43 articles.
1. Implication of DPD deficiency in severe or lethal toxicities after 5-fluorouracil and capecitabine-based chemotherapies;Ciccolini;Cancer Res.,2005
2. A big data approach to the concordance of the toxicity of pharmaceuticals in animals and humans;Clark;Regul. Toxicol. Pharmacol.,2018
3. Controlling epithelial polarity: a human enteroid model for host-pathogen interactions;Co;Cell Rep.,2019
4. Lessons learned from the fate of AstraZeneca’s drug pipeline: a five-dimensional framework;Cook;Nat. Rev. Drug Discov.,2014
5. Cytotoxicity effects of amiodarone on cultured cells;El Golli-Bennour;Exp. Toxicol. Pathol.,2012
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