Validation study of a new reconstructed human epidermis model EPiTRI for in vitro skin irritation test according to OECD guidelines

Author:

Liao Chih-Ching,Wu Cheng-Yi,Lin Meng-Hsueh,Hsieh Feng-Koo,Hsu Lih-Tao,Chang Shiun-Yin,Chen Kuan-Jen,Huang Hui-Ting,Hsu Hui-Chun,Lin Chiu-Hsing,Lin Pei-Ju,Lai Huey-Min,Kojima Hajime,Todo Hiroaki,Lin Sung-Jan,Li Jih-Heng,Chen Wannhsin

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference29 articles.

1. A catch-up validation study on reconstructed human epidermis (SkinEthicTM RHE) for full replacement of the Draize skin irritation test;Alépée;Toxicol. in Vitro,2010

2. In vitro testing of tensides employing monolayer cultures: a comparison with results of patch tests on human volunteers;Benassi;Contact Dermatitis,1999

3. In vitro acute skin irritancy of chemicals using the validated EPISKIN model in a tiered strategy - results and performances with 184 cosmetic ingredients;Cotovio;AATEX,2007

4. Expression of keratin K14 in the epidermis and hair follicle: insights into complex programs of differentiation;Coulombe;J. Cell Biol.,1989

5. The epiCS® Skin Irritation Test (SIT) Method;Engelking,2017

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