A high-throughput dual parameter assay for assessing drug-induced mitochondrial dysfunction provides additional predictivity over two established mitochondrial toxicity assays

Author:

Hynes James,Nadanaciva Sashi,Swiss Rachel,Carey Conn,Kirwan Sinead,Will Yvonne

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference55 articles.

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4. A high-throughput respirometric assay for mitochondrial biogenesis and toxicity;Beeson;Anal. Biochem.,2010

5. The anti-inflammatory drug, nimesulide (4-nitro-2-phenoxymethane-sulfoanilide), uncouples mitochondria and induces mitochondrial permeability transition in human hepatoma cells: protection by albumin;Berson;J. Pharmacol. Exp. Ther.,2006

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