Bile salts regulate CYP7A1 expression and elicit a fibrotic response and abnormal lipid production in 3D liver microtissues

Author:

Messner Catherine Jane,Mauch Linda,Suter-Dick Laura

Funder

Swiss Centre for Applied Human Toxicology

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference68 articles.

1. Bile acids increase proinflammatory gene expression in hepatocytes;Allen;FASEB J.,2010

2. Bile acids induce inflammatory genes in hepatocytes;Allen;Am. J. Pathol.,2011

3. Oxidative stress plays a major role in chlorpromazine-induced cholestasis in human HepaRG cells;Anthérieu;Hepatology,2013

4. Impact of inflammation on chlorpromazine-induced cytotoxicity and cholestatic features in HepaRG cells;Azzi;Drug Metab. Dispos.,2014

5. Bile acids: regulation of synthesis;Chiang;J. Lipid Res.,2009

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