The cytotoxic effects of VE-3N, a novel 1,4-dihydropyridine derivative, involve the mitochondrial bioenergetic disruption via uncoupling mechanisms

Author:

Marín-Prida Javier,Pardo Andreu Gilberto L.,Rossignoli Camila Pederiva,Durruthy Michael González,Rodríguez Estael Ochoa,Reyes Yamila Verdecia,Acosta Roberto Fernández,Uyemura Sergio A.,Alberici Luciane C.

Funder

CAPES-Brazil/MES-Cuba

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference55 articles.

1. Antioxidant activity of 1,4-dihydropyridine derivatives in beta-carotenemethyl linoleate, sunflower oil and emulsions;Abdalla;Food Chem.,1999

2. Mitochondrial regulation of cell cycle and proliferation;Arciuch;Antioxid. Redox Signal,2012

3. Development of small-molecule P-gp inhibitors of the N-benzyl 1,4-dihydropyridine type: novel aspects in SAR and bioanalytical evaluation of multidrug resistance (MDR) reversal properties;Baumert;Bioorg. Med. Chem.,2013

4. Modulation of the mitochondrial cyclosporin A-sensitive permeability transition pore by the proton electrochemical gradient. Evidence that the pore can be opened by membrane depolarization;Bernardi;J. Biol. Chem.,1992

5. 4,6-Dinitro-o-cresol uncouples oxidative phosphorylation and induces membrane permeability transition in rat liver mitochondria;Castilho;Int. J. Biochem. Cell Biol.,1997

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