Effects of microneedle length, density, insertion time and multiple applications on human skin barrier function: Assessments by transepidermal water loss

Author:

Gomaa Yasmine A.,Morrow Desmond I.J.,Garland Martin J.,Donnelly Ryan F.,El-Khordagui Labiba K.,Meidan Victor M.

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference24 articles.

1. Skin penetration enhancement by a microneedle device (Dermaroller®) in vitro: dependency on needle size and applied formulation;Badran;Eur. J. Pharm. Sci.,2009

2. In vivo assessment of safety of microneedle arrays in human skin;Bal;Eur. J. Pharm. Sci.,2008

3. Birchall, J.C., Clemo, R., Anstey, A., John, D.N., in press. Microneedles in clinical practice-an exploratory study into the opinions of healthcare professionals and the public. Pharm. Res.

4. Transepidermal water loss does not correlate with skin barrier function in vitro;Chilcott;J. Invest. Dermatol.,2002

5. Microneedle arrays allow lower microbial penetration than hypodermic needles in vitro;Donnelly;Pharm. Res.,2009

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