The consequence of regional gradients of P-gp and CYP3A4 for drug-drug interactions by P-gp inhibitors and the P-gp/CYP3A4 interplay in the human intestine ex vivo-Reference-Cited by-同舟云学术

The consequence of regional gradients of P-gp and CYP3A4 for drug-drug interactions by P-gp inhibitors and the P-gp/CYP3A4 interplay in the human intestine ex vivo

Published:2017-04 Issue: Volume:40 Page:26-33
ISSN:0887-2333
Container-title:Toxicology in Vitro
language:en
Short-container-title:Toxicology in Vitro

Author:

Li Ming,de Graaf Inge A.M.,van de Steeg Evita,de Jager Marina H.,Groothuis Geny M.M.

Funder

China Scholarship Council

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference41 articles.

1. Intestinal drug absorption and metabolism in cell cultures: Caco-2 and beyond;Artursson;Pharm. Res.,1997

2. Brain microvessel endothelial cell culture systems;Audus,1996

3. The drug transporter-metabolism alliance: uncovering and defining the interplay;Benet;Mol. Pharm.,2009

4. Investigation of drug metabolism in various segments of small intestine in the rat;Bojcsev;Acta Physiol. Hung.,2013

5. Predicting carrier-mediated hepatic disposition of rosuvastatin in man by scaling from individual transfected cell-lines in vitro using absolute transporter protein quantification and PBPK modeling;Bosgra;Eur. J. Pharm. Sci.,2014

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