Poly(lactide-co-glycolide) microspheres containing bupivacaine: comparison between gamma and beta irradiation effects

Author:

Montanari L,Cilurzo F,Selmin F,Conti B,Genta I,Poletti G,Orsini F,Valvo L

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference13 articles.

1. European Guideline 3AQ4a, The use of ionizing radiation in the manufacture of medicinal products (6/1992), Official Publications of the European Communities, 1992.

2. European Guideline CPMP/QWP/054/98 corr, Decision trees for the selection of the sterilization method (4/2000) annex to Note for guidance on development pharmaceutics, Official Publications of the European Communities, 2000.

3. Comparison of electron beam irradiation with gamma processing for medical packaging materials;Woo;Radiat. Phys. Chem.,2002

4. Influence of irradiation sterilization on polymers used as a drug carriers—a review;Sintzel;Drug Dev. Ind. Pharm.,1997

5. Tetracycline-HCl-loaded poly(dl-lactide-co-glycolide) microspheres prepared by a spray drying technique: influence of γ-radiation on radical formation and polymer degradation;Bittner;J. Controlled Release,1999

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