Virtual screening of intestinal drug permeability

Author:

Stenberg Patric,Luthman Kristina,Artursson Per

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference93 articles.

1. Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings;Lipinski;Adv. Drug Deliv. Rev.,1997

2. Prodrugs revisited: The “Ad Hoc” approach as a complement to ligand design;Testa;Med. Res. Rev.,1996

3. Intestinal drug absorption and metabolism in cell cultures: Caco-2 and beyond;Artursson;Pharm. Res.,1997

4. Automated absorption assessment using Caco-2 cells cultured on both sides of polycarbonate membranes;Garberg;Pharm. Res.,1999

5. Automation, reliability and limitations of Caco-2 intestinal permeability screening for selection of well-absorbed drug candidates, Early ADME and toxicology in drug discovery;Morrison,1998

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