Evolution of Experimental Models of the Liver to Predict Human Drug Hepatotoxicity and Efficacy

Author:

Vernetti Lawrence A.,Vogt Andreas,Gough Albert,Taylor D. Lansing

Publisher

Elsevier BV

Subject

Hepatology

Reference71 articles.

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2. Quantitative and systems pharmacology in the post-genomic era: new approaches to discovering drugs and understanding therapeutic mechanisms. In an NIH white paper by the QSP workshop group – October, 2011;Sorger,2011

3. Pharmaceutical innovation in the 21st century: new drug approvals in the first decade, 2000-2009;Kaitin;Clin Pharmacol Ther,2011

4. How can we improve our understanding of cardiovascular safety liabilities to develop safer medicines?;Laverty;Br J Pharmacol,2011

5. Scientific and regulatory reasons for delay and denial of FDA approval of initial applications for new drugs, 2000-2012;Sacks;JAMA,2014

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