A vaccine containing highly purified virus particles in adjuvant provides high level protection against genital infection and disease in guinea pigs challenged intravaginally with homologous and heterologous strains of herpes simplex virus type 2

Author:

Bernstein David I.,Morello Christopher S.,Cardin Rhonda D.,Bravo Fernando J.,Kraynyak Kimberly A.,Spector Deborah H.ORCID

Funder

NIH NIAID

King Abdulaziz City for Science and Technology

NIAID

Publisher

Elsevier BV

Subject

Infectious Diseases,Public Health, Environmental and Occupational Health,General Veterinary,General Immunology and Microbiology,Molecular Medicine

Reference39 articles.

1. Seroprevalence of herpes simplex virus types 1 and 2–United States, 1999–2010;Bradley;J Infect Dis,2014

2. Epidemiology, clinical presentation, and antibody response to primary infection with herpes simplex virus type 1 and type 2 in young women;Bernstein;Clin Infect Dis,2013

3. Prevalence of sexually transmitted infections and bacterial vaginosis among women in sub-Saharan Africa: an individual participant data meta-analysis of 18 HIV prevention studies;Torrone;PLoS Med,2018

4. Effect of genital herpes on cervicovaginal HIV shedding in women co-infected with HIV AND HSV-2 in Tanzania;Todd;PLoS ONE,2013

5. Herpes simplex virus and HIV: genital infection synergy and novel approaches to dual prevention;Thurman;Int J STD AIDS,2012

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