Phase II randomized, double-blinded comparison of a single high dose (5×108 TCID50) of modified vaccinia Ankara compared to a standard dose (1×108 TCID50) in healthy vaccinia-naïve individuals

Author:

Frey Sharon E.,Winokur Patricia L.,Hill Heather,Goll Johannes B.,Chaplin Paul,Belshe Robert B.

Publisher

Elsevier BV

Subject

Infectious Diseases,Public Health, Environmental and Occupational Health,General Veterinary,General Immunology and Microbiology,Molecular Medicine

Reference24 articles.

1. Smallpox and its eradication;Fenner,1988

2. ACAM2000™ Smallpox Vaccine, Vaccines and Related Biological Products Advisory Committee (VRBPAC) Briefing Document; April 18, 2007 [Internet] [cited August 1, 2013], 70p. Available from: http://www.fda.gov/ohrms/dockets/ac/07/briefing/2007-4292b2-02.pdf.

3. The smallpox vaccination strain MVA: marker, genetic structure, experience gained with the parenteral vaccination and behavior in organisms with a debilitated defence mechanism;Mayr;Zentralbl Bakteriol,1978

4. MVA vaccination against smallpox: clinical tests with an attenuated live vaccinia virus strain (MVA);Stickl;Dtsch Med Wochenschr,1974

5. The complete genomic sequence of the modified vaccinia Ankara strain: comparison with other orthopox viruses;Antoine;Virology,1998

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