Nile Red fluorescence spectrum decomposition enables rapid screening of large protein aggregates in complex biopharmaceutical formulations like influenza vaccines

Author:

Sahin Ziya,Akkoc Senem,Neeleman Ronald,Haines Jonathan,Kayser Veysel

Funder

Sanofi-Pasteur

Publisher

Elsevier BV

Subject

Infectious Diseases,Public Health, Environmental and Occupational Health,General Veterinary,General Immunology and Microbiology,Molecular Medicine

Reference48 articles.

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2. Quantitative determination of the surfactant-induced split ratio of influenza virus by fluorescence spectroscopy;Lee;Hum Vaccines Immunother,2016

3. Orthogonal inactivation of influenza and the creation of detergent resistant viral aggregates: towards a novel vaccine strategy;Belanger;Virol J,2012

4. The virosome concept for influenza vaccines;Huckriede;Vaccine,2005

5. Biopharmaceutical formulation;Lee;Curr Opin Biotechnol,2000

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