Increased expression and immunogenicity of HIV-1 protease following inactivation of the enzymatic activity-Reference-Cited by-同舟云学术

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Increased expression and immunogenicity of HIV-1 protease following inactivation of the enzymatic activity

Published:2011-01 Issue:4 Volume:29 Page:839-848
ISSN:0264-410X
Container-title:Vaccine
language:en
Short-container-title:Vaccine

Author:

Hallengärd David,Haller B. Kristian,Petersson Sarah,Boberg Andreas,Maltais Anna-Karin,Isaguliants Maria,Wahren Britta,Bråve Andreas

Funder

EU programs NGIN (Health-F3-2008-201433), AVIP (LSHP-CT-2004-503487)

Europrise (LSHP-CT-2006-037611)

Publisher

Elsevier BV

Subject

Infectious Diseases,Public Health, Environmental and Occupational Health,General Veterinary,General Immunology and Microbiology,Molecular Medicine

Reference36 articles.

1. Heterologous protection against influenza by injection of DNA encoding a viral protein;Ulmer;Science,1993

2. Protection against a lethal influenza virus challenge by immunization with a haemagglutinin-expressing plasmid DNA;Robinson;Vaccine,1993

3. CD8+ T-cell responses to different HIV proteins have discordant associations with viral load;Kiepiela;Nat Med,2007

4. Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome;Koup;J Virol,1994

5. Antiviral pressure exerted by HIV-1-specific cytotoxic T lymphocytes (CTLs) during primary infection demonstrated by rapid selection of CTL escape virus;Borrow;Nat Med,1997

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1. Enzymatic activity of HIV-1 protease defines migration of tumor cells in vitro and enhances their metastatic activity in vivo;Biochimie;2024-08

2. HIV-1 Protease as DNA Immunogen against Drug Resistance in HIV-1 Infection: DNA Immunization with Drug Resistant HIV-1 Protease Protects Mice from Challenge with Protease-Expressing Cells;Cancers;2022-12-30

3. DNA immunization site determines the level of gene expression and the magnitude, but not the type of the induced immune response;PLOS ONE;2018-06-04

4. Codon optimization and improved delivery/immunization regimen enhance the immune response against wild-type and drug-resistant HIV-1 reverse transcriptase, preserving its Th2-polarity;Scientific Reports;2018-05-24

5. Fusion to Flaviviral Leader Peptide Targets HIV-1 Reverse Transcriptase for Secretion and Reduces Its Enzymatic Activity and Ability to Induce Oxidative Stress but Has No Major Effects on Its Immunogenic Performance in DNA-Immunized Mice;Journal of Immunology Research;2017

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