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Marek’s disease herpesvirus vaccines integrate into chicken host chromosomes yet lack a virus-host phenotype associated with oncogenic transformation

  • Published:2016-11 Issue:46 Volume:34 Page:5554-5561
  • ISSN:0264-410X
  • Container-title:Vaccine
  • language:en
  • Short-container-title:Vaccine

Author:

McPherson Marla C.,Cheng Hans H.,Delany Mary E.

Funder

USDA National Institute of Food and Agriculture

National Research Support Program-8

Multi-State Research Projects NC-1170

NE-1334

Publisher

Elsevier BV

Subject

Infectious Diseases,Public Health, Environmental and Occupational Health,General Veterinary,General Immunology and Microbiology,Molecular Medicine

Reference58 articles.

1. Agent of Marek’s disease in tissue culture;Churchill;Nature,1967

2. Herpes-type virus isolated in cell culture from tumors of chickens with Marek’s disease. II. Studies in vivo;Churchill;J Natl Cancer Inst,1968

3. Status of Marek’s disease virus in established lymphoma cell lines: herpesvirus integration is common;Delecluse;J Virol,1993

4. Chromosomal integration of an avian oncogenic herpesvirus reveals telomeric preferences and evidence for lymphoma clonality;Robinson;Herpesviridae,2010

5. Temporal kinetics of Marek’s disease herpesvirus: integration occurs early after infection in both B and T cells;Robinson;Cytogenet Genome Res,2014
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