Comparative studies on in vitro expression and in vivo immunogenicity of supercoiled and open circular forms of plasmid DNA vaccines

Author:

Pillai Vinod Bhaskara,Hellerstein Michael,Yu Tianwei,Amara Rama Rao,Robinson Harriet L.

Publisher

Elsevier BV

Subject

Infectious Diseases,Public Health, Environmental and Occupational Health,General Veterinary,General Immunology and Microbiology,Molecular Medicine

Reference12 articles.

1. Evaluation of degradation pathways for plasmid DNA in pharmaceutical formulations via accelerated stability studies;Evans;J Pharm Sci,2000

2. CBER. Draft Guidance of Considerations for Plasmid DNA Vaccines for Infectious Disease Indications. Biotechnology Law Report 2005. 2005; 24 (3): 304–11.

3. Improved downstream process for the production of plasmid DNA for gene therapy;Urthaler;Acta Biochim Pol,2005

4. DNA/MVA vaccine for HIV type 1: effects of codon-optimization and the expression of aggregates or virus-like particles on the immunogenicity of the DNA prime;Smith;AIDS Res Hum Retroviruses,2004

5. Induction of CD8+T cells using heterologous prime-boost immunisation strategies;Schneider;Immunol Rev,1999

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