Complement-Mediated Activation of the NLRP3 Inflammasome and Its Inhibition by AAV-Mediated Delivery of CD59 in a Model of Uveitis

Author:

Kumar Binit,Cashman Siobhan M.,Kumar-Singh Rajendra

Funder

NIH/NEI

Department of Defense/CDMRP

Ellison Foundation

Publisher

Elsevier BV

Subject

Drug Discovery,Pharmacology,Genetics,Molecular Biology,Molecular Medicine

Reference38 articles.

1. Uveitis: a potentially blinding disease;Durrani;Ophthalmologica,2004

2. Pharmacologic treatment of noninfectious uveitis;Knickelbein;Handb. Exp. Pharmacol.,2017

3. Autoimmune uveitis: clinical, pathogenetic, and therapeutic features;Prete;Clin. Exp. Med.,2016

4. A new model of autoimmune disease. Experimental autoimmune uveoretinitis induced in mice with two different retinal antigens;Caspi;J. Immunol.,1988

5. Pathology of experimental autoimmune uveoretinitis in mice;Chan;J. Autoimmun.,1990

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