Imaging CAR T Cell Trafficking with eDHFR as a PET Reporter Gene

Author:

Sellmyer Mark A.,Richman Sarah A.,Lohith Katheryn,Hou Catherine,Weng Chi-Chang,Mach Robert H.,O’Connor Roddy S.,Milone Michael C.,Farwell Michael D.

Funder

NIH Office of the Director Early Independence Award

Burroughs Wellcome Fund Career Award for Medical Scientists

RSNA Resident Research Award

NIH/NIBIB

St. Baldrick’s Foundation Scholar Award

CHOP Cancer Center K12

NIH/NCI

Stand Up to Cancer

National Center for Advancing Translational Science

NIH

RSNA Research Scholar Grant

American Cancer Society

Publisher

Elsevier BV

Subject

Drug Discovery,Pharmacology,Genetics,Molecular Biology,Molecular Medicine

Reference38 articles.

1. Chimeric antigen receptor therapy;June;N. Engl. J. Med.,2018

2. Molecular imaging to guide systemic cancer therapy: Illustrative examples of PET imaging cancer biomarkers;Pantel;Cancer Lett.,2017

3. Imaging approaches to optimize molecular therapies;Weissleder;Sci. Transl. Med.,2016

4. PET imaging for gene & cell therapy;Collins;Curr. Gene Ther.,2012

5. Human pharmacokinetic and dosimetry studies of [18F]FHBG: a reporter probe for imaging herpes simplex virus type-1 thymidine kinase reporter gene expression;Yaghoubi;J. Nucl. Med.,2001

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