Ex Vivo Selection and Expansion of Cells Based on Expression of a Mutated Inosine Monophosphate Dehydrogenase 2 after HIV Vector Transduction: Effects on Lymphocytes, Monocytes, and CD34+ Stem Cells

Author:

Yam Priscilla,Jensen Michael,Akkina Ramesh,Anderson Joseph,Villacres Maria C.,Wu Jerry,Zaia John A.,Yee Jiing-Kuan

Publisher

Elsevier BV

Subject

Drug Discovery,Pharmacology,Genetics,Molecular Biology,Molecular Medicine

Reference34 articles.

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3. A gene transfer strategy for making bone marrow cells resistant to trimetrexate;Spencer;Blood,1996

4. Retroviral vectors containing a variant dihydrofolate reductase gene for drug protection and in vivo selection of hematopoietic cells;Allay;Stem Cells,1998

5. Genetic protection of repopulating hematopoietic cells with an improved MDR1-retrovirus allows administration of intensified chemotherapy following stem cell transplantation in mice;Carpinteiro;Int. J. Cancer,2002

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