An RNAi therapeutic targeting hepatic DGAT2 in a genetically obese mouse model of nonalcoholic steatohepatitis-Reference-Cited by-同舟云学术

An RNAi therapeutic targeting hepatic DGAT2 in a genetically obese mouse model of nonalcoholic steatohepatitis

Published:2021-11 Issue: Volume: Page:
ISSN:1525-0016
Container-title:Molecular Therapy
language:en
Short-container-title:Molecular Therapy

Author:

Yenilmez Batuhan^ORCID,Wetoska Nicole^ORCID,Kelly Mark^ORCID,Echeverria Dimas,Min Kyounghee^ORCID,Lifshitz Lawrence,Alterman Julia F.,Hassler Matthew R.^ORCID,Hildebrand Samuel^ORCID,DiMarzio Chloe,McHugh Nicholas,Vangjeli Lorenc^ORCID,Sousa Jacquelyn,Pan Meixia,Han Xianlin,Brehm Michael A.^ORCID,Khvorova Anastasia^ORCID,Czech Michael P.^ORCID

Funder

American Heart Association

National Institutes of Health

Publisher

Elsevier BV

Subject

Drug Discovery,Pharmacology,Genetics,Molecular Biology,Molecular Medicine

Reference97 articles.

1. The economic and clinical burden of nonalcoholic fatty liver disease in the United States and Europe;Younossi;Hepatology,2016

2. Global epidemiology of nonalcoholic fatty liver disease—meta-analytic assessment of prevalence, incidence, and outcomes;Younossi;Hepatology,2016

3. Risks and clinical predictors of cirrhosis and hepatocellular carcinoma diagnoses in adults with diagnosed NAFLD: real-world study of 18 million patients in four European cohorts;Alexander;BMC Med.,2019

4. Effect of adipose tissue insulin resistance on metabolic parameters and liver histology in obese patients with nonalcoholic fatty liver disease;Lomonaco;Hepatology,2012

5. Modeling the epidemic of nonalcoholic fatty liver disease demonstrates an exponential increase in burden of disease;Estes;Hepatology,2018

Cited by 29 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Combined structure-based virtual screening and machine learning approach for the identification of potential dual inhibitors of ACC and DGAT2;International Journal of Biological Macromolecules;2024-10

2. DGAT2 Plays a Crucial Role to Control ESRRAPROX1 Transcriptional Network to Maintain Hepatic Mitochondrial Sustainability;Diabetes & Metabolism Journal;2024-09-30

3. HFD Feeding for Seven Months Abolishes STING Disruption-driven but not Female Sex-based Protection against Hepatic Steatosis and Inflammation in Mice;The Journal of Nutritional Biochemistry;2024-09

4. DGAT1 and DGAT2 Inhibitors for Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) Management: Benefits for Their Single or Combined Application;International Journal of Molecular Sciences;2024-08-21

5. The Identification of Key Genes and Biological Pathways in Cardiac Arrest by Integrated Bioinformatics and Next Generation Sequencing Data Analysis;2024-08-19