Melatonin Induction of APP Intracellular Domain 50 SUMOylation Alleviates AD through Enhanced Transcriptional Activation and Aβ Degradation-Reference-Cited by-同舟云学术

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Melatonin Induction of APP Intracellular Domain 50 SUMOylation Alleviates AD through Enhanced Transcriptional Activation and Aβ Degradation

Published:2021-01 Issue:1 Volume:29 Page:376-395
ISSN:1525-0016
Container-title:Molecular Therapy
language:en
Short-container-title:Molecular Therapy

Author:

Liu Yen-Chen,Hsu Wei-Lun,Ma Yun-Li,Lee Eminy H.Y.

Funder

Ministry of Science and Technology

Academia Sinica

IBMS

Academia Sinica in Taiwan

Publisher

Elsevier BV

Subject

Drug Discovery,Pharmacology,Genetics,Molecular Biology,Molecular Medicine

Reference47 articles.

1. Small things matter: Implications of APP intracellular domain AICD nuclear signaling in the progression and pathogenesis of Alzheimer’s disease;Bukhari;Prog. Neurobiol.,2017

2. Amyloid-beta precursor protein processing in neurodegeneration;Wilquet;Curr. Opin. Neurobiol.,2004

3. The intracellular domain of the β-amyloid precursor protein is stabilized by Fe65 and translocates to the nucleus in a Notch-like manner;Kimberly;J. Biol. Chem.,2001

4. A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60;Cao;Science,2001

5. An overview of APP processing enzymes and products;Chow;Neuromolecular Med.,2010

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