Muscle-Directed Delivery of an AAV1 Vector Leads to Capsid-Specific T Cell Exhaustion in Nonhuman Primates and Humans-Reference-Cited by-同舟云学术

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Muscle-Directed Delivery of an AAV1 Vector Leads to Capsid-Specific T Cell Exhaustion in Nonhuman Primates and Humans

Published:2020-03 Issue:3 Volume:28 Page:747-757
ISSN:1525-0016
Container-title:Molecular Therapy
language:en
Short-container-title:Molecular Therapy

Author:

Gernoux Gwladys,Gruntman Alisha M.,Blackwood Meghan,Zieger Marina,Flotte Terence R.,Mueller Christian

Funder

National Institutes of Health

National Heart, Lung, and Blood Institute

Gene Therapy Resource Program

Alpha-1 Foundation

AGTC

Publisher

Elsevier BV

Subject

Drug Discovery,Pharmacology,Genetics,Molecular Biology,Molecular Medicine

Reference81 articles.

1. Robust systemic transduction with AAV9 vectors in mice: efficient global cardiac gene transfer superior to that of AAV8;Inagaki;Mol. Ther.,2006

2. Comparative study of liver gene transfer with AAV vectors based on natural and engineered AAV capsids;Wang;Mol. Ther.,2015

3. Gene therapy vectors based on adeno-associated virus type 1;Xiao;J. Virol.,1999

4. Several log increase in therapeutic transgene delivery by distinct adeno-associated viral serotype vectors;Chao;Mol. Ther.,2000

5. Systemic delivery of genes to striated muscles using adeno-associated viral vectors;Gregorevic;Nat. Med.,2004

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